Coutinho missed Liverpool's start to the season with a back problem but managed to appear for Brazil during the worldwide break.
Though Mignolet wasn't the one to blame for the loss, Liverpool's heavy, 5-0 defeat to Manchester City has further helped to fuel rotation talk, and The Liverpool Echo now think there's a good chance Karius plays on Wednesday when Liverpool travel to Spain to face Sevilla.
Defending In Numbers is a new Deezer Originals football podcast, created by Squawka.
But he did play twice for Brazil in the recent worldwide break and rejoined his Reds team-mates in training at Melwood late last week.
"Klavan has not set the world alight as a Liverpool player and, when you're going to the Etihad, you want your back four to be confident and connected and know where each other is".
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"It [leaving Coutinho out] was a decision made with the season in mind. He came back from a long flight, after two substitute appearances and three weeks without training", Klopp said in his pre-Sevilla press conference.
The Senegalese forward misses next Saturday's home Premier League clash against Burnley then back-to-back visits to Leicester in the Carabao Cup and league - but he will be available for the Sevilla game.
Those are the days, it has often felt, when champions show their true colours in the Premier League.
"We've scored a lot of goals already this season, and the players on the pitch have played the kind of passes Phil can play".
"Emre Can really struggled when he played in the middle of the back three and didn't look solid at all", Carragher said speaking on Sky Sports after the game.
TCU Horned Frogs at Arkansas Razorbacks Start Time, College Football Odds
Quarterback Kenny Hill threw for 206 yards and made four touchdowns helping TCU take a comfortable lead early on in that game. Arkansas played clean last season against TCU , finishing the double-overtime affair with no turnovers.