Ali started tentatively and his first boundary came after facing his first 15 balls.
Earlier, England powered their way to a seven-wicket victory in Manchester after current Test 'keeper Jonny Bairstow made the most of his opportunity in colours with a run-a-ball ton at the top of the order.
Ali, who arrived with England 210-5 and wobbling at the County Ground, devastated the West Indian bowling with the second fastest ODI century by an Englishman. "I thought we were in a bit of trouble, then we lost those three wickets and we both had to rebuild a bit". Joe Root was dismissed soon after that and Chris Woakes joined Ali in the middle.
Ali s six-hitting assault really got going as England scored a remarkable 50 runs in two overs - the 45 and 46th of their innings.
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This channel is famous in India for telecasting the every live cricket match played by Indian cricket team. Till the end of the match , James Faulkner tried his best and reached 32 runs in 25 balls.
He eventually holed out off spinner Ashley Nurse and walked off to a standing ovation from a near-capacity crowd.
He went to his 50 off 41 balls with three sixes in an over from former Worcestershire overseas player Miguel Cummins which cost 25 runs.
England captain Eoin Morgan, whose poor run of form with the bat continued with a golden duck, hailed Ali s man-of-the-match effort. "I felt me and Woakesy had got to a situation where we had got ourselves in and it was time to press the button and play a few shots and the ground is a good size for someone like myself - it's not a massive hit for six", Moeen said.
"Most people would be excited to have a guy like Andre Russell (who is due to complete a one-year ban for a missed drugs tests in January) also champing at the bit to play worldwide cricket".
West Indies opener Evin Lewis hit two sixes in David Willey s first over before the left-arm quick had him caught at mid-on by Ali.