Stephen Sarfo, who was voted as the man-of-the-match scored a brace for the Black Stars, while Vincent Atinga and Winful Cobbinah scored a goal each for the hosts.
Nigeria pulled a consolation goal in added time as Rabiu Ali flawless inched free kick beat Ghana's Joseph Addo at his near post.
The local Black Stars emerged 2-0 winners over Niger, a few hours after Nigeria had recorded a 1-0 win over Benin in the other Semi- final match of the Competition.
The fans, on Monday in Abakaliki, said that several factors contributed to the team's loss and advised the NFF to address them instead of overhauling the team.
Ezenwa kept clean sheet in Nigeria's first four matches before poor defending exposed him to the four goals he conceded last night.
The defender who comically added that despite the fact that Nigeria lost the match that the country's jollof rice is still better than that of Ghana.
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In the 33rd minute, goalkeeper Ezenwa Ikechukwu pulled a great save to deny Isaac Twum.
"The players have been together for long and duly qualified for the CHAN competition".
Kano Pillars' Ali got a consolation goal for Nigeria deep into stoppage time but Ghana had already rolled out the drums for a well deserved victory.
"It was a good lesson for us", said Salisu after the final between two long-time rivals.
"To be fair to the team, they went for an global tournament without camping, played six matches, five of which they did not concede a goal until the final match".
The Eagles had a chance of their own in the 67th minute but Osas Okoro shot his free kick straight into the Black Stars wall of defence.