All 103 local Sears and Kmarts, including the Ocala and Bellview locations, will shutter by May.
Closeout sales will begin next week with all locations shuttered by May.
A spokesperson for Sears Holdings declined to say how many employees will be affected by the closings.
The new round of closures comes after Sears announced it would close 250 stores a year ago, including the Malone location.
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Sears, once one of the country's most successful retailers, has struggled with the rise of e-commerce and some management missteps.
The company said the closures are part of an ongoing effort to "right size" its store footprint.
In 2006, the company operated more than 3,000 locations in USA and a few hundred in Canada.
The department store portion of the business will remain open until April but the auto center will close later this month, according to the statement.