Blood test could help screen for eight common cancers


"This interesting research is a step towards being able to do this earlier than is now possible", he said. One startup, Grail Bio, has raised over $1 billion in pursuit of a single blood test for many cancers.

"This is a proof-of-concept", said Dr. Anne Marie Lennon, one of the researchers on the work. "This has the potential to substantially impact patients".

Think about breast cancer.

A team of scientists at John Hopkins University, who published the study in journal Science on Thursday, said the test could be available to patients in the next few years.

A portion of the blood tests at present used to analyze growth incorporate finish blood tally, blood protein testing, tumor marker tests, and flowing tumor cell tests. "That could save their life", said study author Nickolas Papadopoulos in an interview with NPR.

While early diagnosis is frequently held up as the first step to more success in treating tumors, including by Cohen and his colleagues, the data for those cancers where early screening tools exist have been more mixed. Patients all had Stage I-III nonmetastatic disease.

"You have to detect smaller and smaller molecules that are swimming in a sea of background noise", Lichtenfeld said. It simultaneously evaluates levels of eight cancer proteins (which account for more than 60 percent of cancer deaths) and the presence of cancer gene mutations from circulating DNA in the blood.

"That's a big move forward", she said. "I'm not going to go to the doctor because the CancerSEEK test told me it was negative", Schiffman says.

Development of the "liquid biopsy" test is still in its early stages. The study claims that even if these results are indeed false positives the specificity rate is still around 99 percent, making it much more accurate than many conventional tests.

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Abstract of the study explains how CancerSEEK operates.

Scientists at a university in the United States have made a breakthrough that could revolutionise the way cancer is diagnosed.

Earlier detection is key to reducing cancer deaths.

However, the team believes that the results of its current research are encouraging.

The work was financed by many foundations, the Mayo Clinic, the National Institutes of Health and Howard Hughes Medical Institute, which provides The Associated Press with funding for health and science coverage. Peter Gibbs, from Australia's Walter and Eliza Hall Institute of Medical Research, were part of the USA -led research team that developed the tests for cancers affecting the ovary, liver, stomach, pancreas, oesophagus, bowel, lung and breast, the facility said in a statement. Twenty percent had smaller, stage 1 tumors. The laboratory was not involved in tests for a new eight-cancer liquid biopsy detection test called CancerSEEK.

They found that the test was able to identify 70 percent of the cancers, with sensitivity ranging from 33 percent for breast cancer to 98 percent for ovarian cancer. The algorithm guessed right 83 percent of the time. False positive rates need to be very low for a cancer detection tests to be considered feasible.

"This is an important study. But there's a long way to go". "Particularly when it comes to identifying what things should cost, we're particularly bad at that", he said.

"Just because we're able to detect a protein, that doesn't mean we'll save everyone's life", he noted.

The test has been shown to reliably detect early stage and curable cancers.