Guardiola says he doesn't expect any revenge attack on the Liverpool bus, in retaliation to last week's attack on the City bus.
"We have 90 minutes and anything can happen".
While Greater Manchester Police will deploy extra officers around the ground as they look to avoid a repeat of the ugly scenes from Anfield last Wednesday.
"We have to score the first one, then make the second one". I'm only happy with the clean sheet.
'We need to come in with the mindset it's 0-0.
"We started the game really well, but we must return to the pitch as soon as possible because on Tuesday we have another big challenge to overcome a result".
"You could see in the second half we were tucked in and it was hard to defend and they came through more than they did in the first half so I don't think we should sit too far back".
Clean sheet crucial for Reds and Oxlade-Chamberlain
Chamberlain, who joined Liverpool from Arsenal in January, put up a standout moment of his career with a stunning strike to put the Reds 2-0 ahead.
"Sometimes we need to play better - myself as well - but you can't deny that some legs are a bit exhausted".
"But we must be together". Two defeats is not easy but it happens to the best teams in the world.
The Sunday Supplement panel assess what went wrong for Manchester City following their 3-2 defeat to Manchester United.
"But in the case of Nico, when a player does what he has done, all we can do is to be close to him because Nico is not just a huge quality but a huge mentality. We know that and the opponents know that".
"I don't know but if we are not able to cope with that psychologically it will be a good lesson for the future".
Manager Jurgen Klopp will issue an injury update when he faces the media at lunchtime.